First trials with nasal spray against Covid-19 start in UK

The first clinical trials of a nasal spray that kills the Covid-19 virus are also starting this month in the UK.

SaNOtize’s so-called Nitric Oxide Nasal Spray (NONS) is designed to kill the virus in the upper respiratory tract, preventing it from incubating and spreading to the lungs. On January 11, the first trials with the nasal spray will begin at St. Peter Hospital in Surrey.

The treatment of the Vancouver-based SaNOtize Research and Development Corp. was already found to be 99.9 percent effective in killing the coronavirus in independent laboratory tests at the Antiviral Research Institute at Utah State University, in the United States.

Additional studies at Colorado State University in rodents infected with Covid-19 showed an average reduction of more than 95 percent within the first day of infection with the virus. The promising nasal spray is also currently undergoing phase 2 studies in Canada and other countries.


“The SaNOtize nasal spray creates a barrier,” Chris Miller, co-founder of SaNOtize, said earlier in a statement. “It contains nitric oxide that prevents and treats early infection by destroying the virus and stunting viral multiplication within the cells in the nose.”

Pankaj Sharma, professor of neurology and director of the Institute of Cardiovascular Research at Royal Holloway (University of London) welcomes the first UK trials of the nasal spray: “Any agent for the treatment of the coronavirus – the virus responsible for Covid-19 – is to be welcomed. The fact that a relatively easy and simple nasal spray could be an effective treatment is welcome news and represents a significant advance in our therapeutic arsenal against this devastating disease. ”

Nitric Oxide

The importance of nitric oxide to the human body and its healing properties were first discovered by, among others, Professor Ferid Murad of Stanford University, for which he was awarded the Nobel Prize in Medicine in 1998. He is now also a board member of SaNOtize.

“Nitric oxide is an incredibly versatile molecule that regulates almost everything in our bodies,” said Murad. “In therapeutic use it has a well-documented safety profile and has been shown to be effective against a wide variety of viruses, bacteria and fungi. I am excited to partner with the SaNOtize team and believe they have a safe technology that could be effective in treating infections, including Covid-19. ”

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