At the beginning of 2021, millions of people around the world will start the corona vaccination.
The previously approved vaccinations from Biontech / Pfizer and Moderna have proven to be highly effective and offer up to 95 percent protection against the disease caused by the novel coronavirus.
However, immunity from the vaccine does not set in immediately. Each of these vaccines requires two vaccinations, which have to be given several weeks apart to ensure reliable and long-lasting protection against the virus.
Although there is some evidence that a first dose can strengthen the body’s defenses against the novel coronavirus, the risk of infection only drops to up to 5 percent after the second vaccination.
As Pfizer CEO Albert Bourla said in December, it would be a “big mistake” to rely on just one shot with his company’s vaccine to protect against the disease. While one vaccination could help bring the pandemic under control, Bourla told reporters that two vaccinations could nearly double protection.
Yes, you can still get Covid-19 after the first injection of a double vaccine
There are already several cases of people who became infected with the coronavirus after the first vaccination. A nurse in California got Covid-19 six days after his first vaccination, and another doctor in the Georgia emergency room got Covid-19 nine days after his first dose of Pfizer’s vaccine.
“I happened to be infected within a few days of being vaccinated,” said Josh Mugele, the ambulance, “but (the vaccination) is still the best tool we have to fight the virus.”
Vaccinated people receive some form of protection from the first vaccination, which usually starts after about two weeks. However, two vaccinations have been shown to be more effective for stronger and longer lasting immunity.
“The second dose gives you an immune response ten times higher than the first dose,” said Moncef Slaoui, Moncef Slaoui, the US chief scientific adviser for the introduction of the vaccine, on the US news program CBS.
Vaccines train the body to fight the coronavirus, and that takes time
The vaccination works quickly, but not immediately. “It will take some time for your body to build a robust immune response that will protect you, and unfortunately that protection won’t come once the needle pierces your skin,” said Wesley Willeford, medical director of disease control at Jefferson County Health Department in Alabama. recently to the US television station WBRC.
“Once you are vaccinated and have received both doses, you still have to wait two to four weeks before you can really think about doing a lot of activities again.”
When the corona vaccines were tested on tens of thousands of volunteers around the world, the scientists relied on a two-dose regimen. Claims that vaccines are up to 95 percent effective at preventing Covid-19 infections are only based on study results with two vaccinations given several weeks apart.
Before measuring the effectiveness of the vaccine, patients waited a week or two after their second vaccination to make sure their vaccinations had enough time to work. Even then, the vaccinations weren’t perfect to prevent every single infection.
The Pfizer / Biontech vaccine is up to 95 percent effective with double vaccination
Pfizer / Biontech’s vaccine is up to 95 percent effective. It consists of two vaccinations given 21 days apart.
According to the US Food and Drug Administration FDA, Pfizer’s first vaccination offers up to 52 percent protection. But it is only a week after the second vaccination that the probability of contracting Covid-19 drops to just 5 percent.
This means that if someone receives Pfizer’s two vaccinations exactly 21 days apart, they shouldn’t expect to be fully protected until about a month (28 days) after the first dose.
Moderna’s results look similar. According to the results of the study, the first vaccination after 14 days can offer good protection, around 90 percent.
But it’s not exactly clear how long this protection lasts, as almost all study participants received a second booster dose 28 days later. Current knowledge shows that two vaccinations protect people almost completely from the most serious, potentially fatal infections.
Further vaccination methods are currently being researched
It is possible that different doses, combinations, or timing of these vaccines could produce better results, or that distributing smaller doses to the population would allow more people to be vaccinated more effectively and quickly. However, these other possibilities have not yet been properly explored.
Scientists in the UK are now conducting a mix-and-match study to see if using a syringe of Pfizer’s mRNA vaccine with a syringe of AstraZeneca viral vector vaccine could provide better protection for people than one single brand alone.
At the moment, the US Food and Drug Administration (FDA) claims that “without adequate data to support such changes in vaccine delivery, we run a significant risk of public health” if any of these untested strategies become widespread Public would be tried.
Delaying the second vaccination is risky, but it could also save some lives
With new, potentially more contagious, variants of the virus now rapidly spreading around the world, UK authorities have decided to try and vaccinate as many people as possible with a single syringe – giving them a bit of protection each.
However, experts say this is still a risky and untested strategy. “We want to act fast, but we need the studies,” Paul Offit, professor of vaccinology at the University of Pennsylvania and director of the Vaccine Education Center, told NewsABC.net.
Stanley Plotkin, a professor at the University of Pennsylvania, recently wrote a letter to the director of the U.S. Center for Disease Control and Prevention. He urged that during a pandemic spiraling out of control in the US, the one-shot strategy could be beneficial.
“It makes sense to try to protect as many people as possible,” he told NewsABC.net. “One dose could offer a lot of protection … in the worst case scenario it will at least reduce the severity of the disease.”
This text has been translated from English. You can find the original here.